Controls experienced reductions in these parameters; however, a larger reduction was noted with calendula.37, Calendula extracts have demonstrated in vitro antibacterial, antiviral, antifungal,7, 38, 39, 40, 41 and immunostimulating properties.42, 43 Cytotoxic, hepatoprotective, spasmogenic, and spasmolytic properties have been demonstrated in in vitro experiments.7, 43, 44, 45 In an animal model, calendula provided protective effects against hepatotoxicity and cisplastin-induced nephrotoxicity.46 Angiogenic activity due to induction of neovascularization was reported with an ethanolic extract and dichloromethane and hexanoic fractions of calendula.47, In a study of mice with B16F-10 melanoma allografts, the antimetastatic effects of calendula were assessed. A preparation can be made by steeping 5 to 10 mL of the herb in 1 cup of boiling water for 10 minutes and then gargled as a mouthwash for oral sores, consumed for its antispasmodic effects, or applied topically for skin conditions. The anti-inflammatory properties of calendula are attributed to triterpenoids.18, Triterpenoid-containing extracts of calendula have been investigated in chemically induced inflammation in mice.7, 12 Calendula extracts alleviated signs of chronic conjunctivitis and other chronic ocular inflammatory conditions in rats19; the extracts also had a systemic anti-inflammatory effect. An ointment containing 5% flower extract in combination with allantoin markedly stimulated epithelialization in surgically induced wounds. Nsonguyo. Because of this, calendula oil, tea, and ointment can be used to treat minor skin and eye infections as well as general skin conditions. We respect your right to privacy. On the basis of histological examination of wound tissue, it was concluded that the ointment increased glycoprotein, nucleoprotein, and collagen metabolism at the site.22 Calendula may help enhance blood flow to the affected area.21 Also, calendula 4% and 5% creams applied for 1 month produced alterations in the levels of antioxidants found in the skin of rats that received ultraviolet-B radiation. Calendula is a native Mediterranean plant that belongs to the daisy plant family Asteraceae. Do not use if you are allergic to Calendula officinalis or to any of this product's inactive ingredients . It takes a vital role in curing skin problems like ulcers and acne. Fever. This is certainly the case when it comes to calendula. Treatment with calendula 200 mg/kg was also found to reduce acute phase protein levels.24, In a murine model, wound closure on day 8 of healing was approximately 90% in rats receiving oral calendula 20 or 100 mg/kg, or topical calendula, compared with 51.5% of those in the control group. When you take a closer look at calendula, you probably wouldn’t be surprised at its health benefits. A study in rats demonstrated that a hydroalcohol extract of C. officinalis did not possess toxic effects on male fertility or during the early and midpregnancy periods in females. A substance made from the flower of the marigold plant Calendula officinalis. Try it on minor first degree burns, blisters, chafing, cuts, scrapes or cracked heels. Also gives a list for special health needs. Natural healers have found calendula ointment uses for many of years. Promoting menstruation. According to Memorial Sloan-Kettering Cancer Center in New York, preliminary studies suggest that calendula does indeed work as an anti-inflammatory but also has anti-viral, anti-parasitic, anti-HIV, anti-tumor, and antibacterial properties. A 2013 review found that calendula has antiseptic, antiviral, and antifungal, and can be used successfully to treat skin conditions. I love using it on my clients and I suggest it if you suffer from dryness, cracked skin, or itching. Potential uses for calendula include the treatment of inflammatory skin disorders, wound healing, and the treatment of other skin conditions. FREE Delivery on your first order shipped by Amazon. The Foundation is supported in entirety through donations provided by Jon Barron and Baseline Nutritionals, Inc. We do not offer medical advice. Flowers often have herbal uses beyond being beautiful to look at. Calendula flower is commonly used for wounds, rashes, infection, inflammation, and many other conditions. While considered mostly side-effect free, people with sensitivities to the aster family of plants may have an allergic reaction. The oil of C. officinalis is used as an anti-inflammatory and a remedy for healing wounds. Potential uses for calendula include the treatment of inflammatory skin disorders, wound healing, and the treatment of other skin conditions. Muscle spasms. So, most of the cosmetic creams and other products have calendula as one of the main ingredients. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. 4.5 out of 5 stars 199. No statistically significant differences existed between treatment groups with regard to acute radiation skin reactions (incidence of 23% with calendula vs 19% with the aqueous cream). This product has not been reviewed by the FDA to determine whether it is safe or effective and is not subject to the quality standards and safety information collection standards that are applicable to most prescription drugs. Slight abnormalities in the hepatic parenchyma were also noted.59 Saponin extracts of C. officinalis are not mutagenic.60 The median lethal dose of calendula flower extract in rats was more than 4.64 g/kg.58. 31, In a study of primiparous women who underwent an episiotomy, calendula ointment applied every 8 hours to the perineal area was associated with improvements in redness, edema, approximation, and ecchymosis compared with standard treatment with betadine.18, In a study of human gingival fibroblasts, calendula 1% to 3% completely inhibited collagen degradation, and calendula 2% to 3% completely inhibited pro-matrix metalloproteinase–2 activity. Calendula is ideal to use for babies and toddlers. There were higher amounts of hydroxyproline in the granuloma tissue of those treated with calendula compared with the controls. In general, patients reported low levels of skin symptoms. This oil can be used as a good massage oil and face cream. The statements found within these pages have not been evaluated by the Food and Drug Administration. You may also use calendula to balance out and normalize your digestive system, which can reduce problems like acid reflux, nausea, and intestinal discomfort caused by inflammation. Scientific Name(s): Calendula officinalis L.Common Name(s): Calendola, Calendula, Garden marigold, Gold bloom, Goudsbloem, Holligold, Maravilla, Marigold, Marybud, Marygold, Nagotki, Neven, Pot marigold, Ringelblume, Souci. It is often used by herbalists for first-degree burns and sunburns as well. Calendula herbal treatments are typically applied topically to help burns, cuts, and bruises heal faster.